Anacetrapib Intermediate 6 - Names and Identifiers
Anacetrapib Intermediate 6 - Physico-chemical Properties
Molecular Formula | C10H14BFO3
|
Molar Mass | 212.03 |
Density | 1.15±0.1 g/cm3(Predicted) |
Boling Point | 324.0±52.0 °C(Predicted) |
pKa | 8.69±0.58(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
Use | This product is for scientific research only and shall not be used for other purposes. |
Anacetrapib Intermediate 6 - Introduction
Boronic acid, [4-fluoro-2-methoxy-5-(1-methylethyl)phenyl]-is an organic compound with the chemical formula C12H16BFO3. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless crystalline solid
-Melting point: about 150-152°C
-Solubility: Soluble in organic solvents such as ethanol, chloroform and dimethyl sulfoxide
-Stability: Stable at room temperature, but may decompose under high temperature or light conditions
Use:
- Boronic acid, [4-fluoro-2-methoxy-5-(1-methylethyl)phenyl]-is an important aromatic compound that can be used as a reaction reagent and intermediate in organic synthesis.
-It can be used for the synthesis of phenylboronic acid lipids, thereby expanding the chemical reactions and synthesis methods of aromatic compounds.
Preparation Method:
- Boronic acid, [4-fluoro-2-methoxy-5-(1-methyllethyl) phenyl]-can be synthesized by the following steps:
1. reacting p-methoxyphenylboronic acid with an organic acid salt of hydrogen fluoride to obtain 4-fluoro-2-methoxyphenylboronic acid.
2. 4-fluoro-2-methoxybenzeneboronic acid is reacted with isopropyl magnesium bromide to obtain Boronic acid, [4-fluoro-2-methoxy-5-(1-methylethyl)phenyl]-.
Safety Information:
-Specific toxicity information for this compound is limited, so please follow laboratory safety procedures when handling.
-Because it is an organic compound, it may irritate the skin, eyes and respiratory system. Therefore, you should wear appropriate protective measures, such as laboratory gloves, goggles and protective masks.
-During storage and handling, avoid contact with strong oxidants and high temperatures to prevent possible decomposition reactions and fire hazards.
Last Update:2024-04-10 22:29:15